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Scientific activity

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Study Tours Abroad:

1996
University of Cologne, Department of Neurosurgery Clinical Unit, Cologne, Germany
– 2 weeks

1998-1999
University of Cologne, Department of Neurosurgery, Clinical Unit,
Neuro-Oncological Laboratory, Cologne, Germany – 1  year DAAD scholarship

2004
Miguel Hernandez University, Institute of Anatomy, Alicante, Spain; – 2 weeks

Successful Research Grants:

  1.  OTKA T-020128/1995; participant, 1996-1999, HUF 1,400,000

            Supervisor: Dr. Péter Molnár, DE OEC, Institute of Pathology

  1.  ETT 350/1996 participant, 1997-1999, HUF 1,500,000

            Supervisor: Dr. György Csécsei, Department of Neurosurgery, Debrecen

  1.  Mecenatura 2004-2006; participant, HUF 750,000

            Supervisor: Dr. Szabolcs Felszeghy, DE OEC, Institute of Anatomy

  1.  ETT: “The role of systemic histopathological aberrancies in early diagnosis of brain

            aneurysms”.  Duration: 2003-2005.  Budget: HUF 3,000,000

            Supervisor: Dr. Álmos Klekner

  1.  OTKA: “The examination of the role of EGFR and intergrins in tumor invasion in intracranial
    tumors”. Duration: 2005-2008. Budget: HUF 6,000,000

            Supervisor: Dr. Álmos Klekner

Number of scientific publications:         24        Number of presentations, posters:        45

Cumulative impact factor:                     53.13   Total citation index (without self-citation): 46

Memberships: 

  • Hungarian Neurosurgery Society
  • Hungarian Neuropathology Society
  • Hungarian Neuro-oncology Society
  • European Neurosurgery Society

Scientific interest:: Neuro-oncological Laboratory

  1. Up-to-date treatment of brain tumors– see literature

Klekner A, Ernestus RI, Röhn G, Molnár P, Csécsei Gy, Klug N: Polyamine metabolism in ependymomas. Path Int, 46, S1: 625, 1996, IF: 0.748

Ernestus RI, Röhn G, Schröder R, Els T, Klekner A, Paschen W, Klug N: Polyamine metabolism in brain tumours: diagnostic relevance of quantitative biochemistry. J Neurol Neurosurg Psychiatry 71: 88-92, 2001, IF: 3.024

Klekner A, Röhn G, Schillinger G, Schröder R, Klug N, Ernestus RI: ODC mRNA as a prognostic factor for recurrence in meningiomas. J Neuro-oncol. 53: 67-75, 2001
IF: 1.435

Klekner A, Ernestus RI, Röhn G, Molnár P, Csécsei Gy, Klug N: Polyamine metabolism in ependymomas. Path Int, 46, S1: 625, 1996, IF: 0.748

Dabasi G, Hauser P, Kertész GP, Balázs G, Karádi Z, Constantin T, Bognar L, Klekner A, Schuler D, Garami M: Imaging of pediatric brain tumors using somatostatin analogue 111Ih-DTPA-D-Phe1-octreotide. Magy Onkol, 2007 51(3):229-234.

Toth J, Egervari K, Klekner A, Bognar L, Szanto J, Nemes Z, Szollosi Z. Analysis of EGFR Gene Amplification,
Protein Over-expression and Tyrosine Kinase Domain Mutation in Recurrent Glioblastoma. Pathol Oncol Res. 2008 Aug 28. (Epub ahead of print). IF: 1.24

Klekner A, Varga I, Bognár L, Hutóczki G, Kenyeres A, Tóth J, Hanzély Z, Scholtz B.: Különböz? invazivitású agydaganatok extracelluláris mátrixának expressziója. J Clin Neurosci. Közlésre elfogadva, 2009.03.

Petrás M., Varga I., Vereb Gy., Szöll?si J., Hutóczki G., Bognár L., Ruszthi P., Kenyeres A., Tóth J., Hanzély Z., Scholtz B., Klekner Á.: Különböz? eredet? malignus agydaganatok invazivitásának panelszer? vizsgálata. Magyar Onkológia, 2009; 53(3):253-8.

2. Development of surgical techniques of degenerative disc pathography – see literature

Csécsei Gy, Klekner A, Sikula J: Posterior lumbar interbody fusion (PLIF) using the bony elements of the dorsal spinal segment. Acta Chir Hun, 36 (1-4): 54-56, 1997

Csécsei Gy, Klekner A, Dobai J, Lajgut A, Sikula J: Posterior interbody fusion using laminectomy bone and transpedicular screw fixation in the treatment of lumbar spondylolisthesis. Surg Neurol, 53 (2-7):  2000, IF: 1.018 – CI: 3

  1. Medicinal treatment of neurosurgical patients – see literature

Gáspár A., Kardos Sz., Andrási M., Klekner Á.: Capillary electrophoresis for the direct determination of cephalosporins in clinical samples. Chromatographia 54: 109-114, 2002 IF: 1.317

Klekner Á., A.Gáspár, S.Kardos, J.Szabó, Gy.Csécsei: Cefazolin prophylaxis in neurosurgery monitored by capillary electrophoresis, J Neurosurg Anesth, 15: 249-254, 2003 IF: 0.739

Klekner A, Bagyi K, Bognar L, Gaspar A, Andrasi M, and Szabo J: Penetration of Cephalosporins into the Sputum in Nosocomial Bronchopneumonia. J Clin Microbiol, 2006 Sep; 44(9):3418-21 IF: 3.44

Andrasi M, Gaspar A, Klekner A: Analysis of cephalosporins in bronchial secretions by capillary electrophoresis after simple pre-treatment. J Chromatogr B Analyt Technol Biomed Life Sci. 2006 Sep 13. IF: 2.175

Bagyi K, Márton I, Szabó J, Andrási M, Gáspár A, Varga I, Bognár L, Klekner A: Efficacy of pre-operative cephalosporin prophylaxis in controlling pathogenic oral bacterial growth in comatose patients. J Med Microbiol. 2008 Jan 57:129-9 IF: 2.18

Bágyi K, Haczku A, Márton I, Szabó J, Gáspár A, Andrási M, Varga I, Tóth J, Klekner A.: Role of pathogenic oral flora in postoperative pneumonia following brain surgery. BMC Infect Dis. 2009 Jun 29; 9(1):104. (Epub ahead of print). IF: 2.54